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Why Culturelle®

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    Why Culturelle®

#1 pediatrician recommended kids brand

Superior Quality Probiotics

Culturelle® Probiotics are designed for your patients using superior-quality ingredients that have been demonstrated safe and effective in human trials, including the #1 clinically studied strain, Lacticaseibacillus rhamnosus GG.

Safety & Efficacy

Culturelle® Probiotics have been used in clinical studies since 1998 and have demonstrated safety and efficacy in all age groups. Read more about the criteria that differentiate probiotics in the context of quality, efficacy, and safety.

Rigorous Quality Control

Culturelle® Probiotics are packaged to ensure the viability of colony-forming units (CFUs) until the end of shelf life without the need for refrigeration.

Higher Standards

Culturelle® Probiotics are produced according to Food and Drug Administration (FDA) Regulation 21 CFR Part 111 and manufactured in compliance with FDA's current Good Manufacturing Practice (cGMPα). Our quality systems are NSF audited regularly for compliance with specific safety, quality, sustainability, or performance standards.

Evidence-Based Ingredients

Culturelle Probiotics® is proud to deliver microbiome-targeting ingredients that have demonstrated efficacy in human trials, including the #1 clinically-studied probiotic, Lacticaseibacillus rhamnosus GG.

Evidence-Based Formulas

Swipe to learn more about our journey to leverage clinical evidence to deliver microbiome-targeted solutions for your patients.

L. rhamnosus GG discovered
Goldin and Gorbach characterize L. rhamnosus GG
Culturelle® Probiotics offers L. rhamnosus GG in a capsule
Adult product delivers shelf-stable L. rhamnosus GG
Culturelle® Kids Packets are introduced
A shelf-stable, unflavored L. rhamnosus GG option for children
Culturelle® is the #1 pediatrician recommended probiotic since 2010
Efficacy, safety and accessibility lead to top recommendation by providers
Culturelle® Kids Chewables introduced
Offering a great tasting probiotic for children
Culturelle® Adult Chewables introduced
Adults deserve a great tasting option too
Culturelle® Kids Packets are upgraded
Evidence-based upgrade to contain 5 Billion CFUs
Culturelle® Baby drops and packets are introduced
Delivering the first Culturelle multistrain formula with #1 (L. rhamnosus GG) and #2 (B. lactis, BB-12®) – the most clinically studied strains in children
Culturelle® Women’s Healthy Balance is formulated by women for women
Offering a multistrain formula including a 4-strain lactobacillus blend for vaginal health
Culturelle® Gummies are made available for kids and adults
Clinically studied Bacillus strains in efficacious amounts for children and adults
Culturelle® offers unique Metabolism + Weight Management support for the microbiome
Leveraging a select Bifidobacterium and B vitamins, combined with L. rhamnosus GG
Culturelle® Advanced Regularity Probiotic & Prebiotic Fiber offers a solution for one of the most common digestive issues
Delivers three clinically proven probiotic strains, including L. rhamnosus GG, a two-strain Lactobacillus combination, and a cold-pressed kiwi extract
Culturelle® launches Abdominal Support & Comfort
Combining human milk oligosaccharides and a clinically studied Bacillus strain, Unique IS-2


We partner with clinicians, scientists, and advocates to advance microbiome science.


Tufts University
Duke University
Kent State University
University of Nebraska
Massachusetts General Hospital
Virginia Commonwealth University
McGuire VA Medical Center
Children’s Hospital, Boston
Nemours Children’s Clinic
and more...

Health Advocacy

NEC Society - Building a world without necrotizing enterocolitis (NEC)

National Eczema Association (NEA) - the voice, the resource and the hub for those living with eczema

Canadian Digestive Health Foundation (CDHF) - Canada’s trusted resource on digestive health.

and more...


American Society for Parenteral and Enteral Nutrition (ASPEN)

AEProBio -creators of the Clinical Guide to Probiotic Products

Council for Responsible Nutrition (CRN)
International Probiotic Association (IPA)
International Scientific Association of Probiotics and Prebiotics (ISAPP)